Ask a Librarian: Novel Coronavirus (COVID-19)

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On December 31, 2019, Chinese health officials announced the existence of a new respiratory illness. The outbreak was linked to a seafood and poultry market in Wuhan City, located in Hubei Province.

Novel Coronavirus (nCoV), a strain of coronavirus which has never been identified in humans before, was temporarily named “2019-nCoV”. It is also known as Wuhan Virus or the Wuhan novel coronavirus (WN-CoV).

According to WHO, coronaviruses (CoV) belong to a larger family of viruses ranging from the common cold to more severe illnesses like Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV)

On February 11, WHO officially named the virus COVID-19.

Here are some resources on coronaviruses and COVID-19 selected by Joule’s Ask a Librarian team using a variety of tools included with a CMA membership or freely available online.

 

Clinical summary from DynaMed

Access DynaMed online or through the mobile app to get concise overviews and detailed recommendations, medical graphics and images, drug information from Micromedex and more.

Novel Coronavirus (2019-nCoV) - excerpt:

  • severe acute respiratory infection caused by novel coronavirus 2019-nCoV first identified in December 2019 in Wuhan, Hubei Province, China1
    • initial infections associated with seafood and animal market
    • human to human transmission confirmed, though route and ease of transmission are unclear
  • 2019-nCoV is a member of beta genus coronaviruses and closely related to SARS-CoV (88% homology reported to bat SARS-like coronavirus virus) (China CDC Weekly 2020 Jan 22)
  • common signs of infection include fever, cough, and shortness of breath1
  • there is no specific antiviral treatment for 2019-nCoV, but supportive care may help to relieve symptoms and should include support of vital organ functions in severe cases1

Topic Summary (CMA members can access full summaries via this link)

 

Clinical information via ClinicalKey

ClinicalKey drives better care by delivering fast, concise answers, and deep access to evidence whenever, wherever you need it. ClinicalKey includes access to 1,000+ textbooks, 600 full-text journals, images, videos and customizable patient handouts across 30+ medical specialties

Novel Coronavirus Information Center  (Elsevier/ClinicalKey) - freely available and current information in English and Mandarin Chinese on the novel coronavirus 2019-nCoV.

In ClinicalKey (CMA members only) search “2019-nCoV” for the latest articles from The Lancet, International Journal of Infectious Diseases, Journal of Infection and more.

Book chapters:

Coronaviruses by Susan I. Gerber and John T. Watson in Goldman-Cecil Medicine, chapter 342, 2164-2167.e2

Coronaviruses, Including Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) in  Stanley Perlman and Kenneth McIntosh Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 155, 2072-2080.e3

 

Free information sources

Articles, article collections and reviews

BMJ - Coronavirus – collection of freely available news articles, opinion, timeline and a BMJ Best Practice summary.

CMAJ – Coronavirus – collection of news articles, selected resources and podcast and podcast transcript featuring February 3rd interview by Dr. Kirsten Patrick, deputy editor for CMAJ, with three infectious disease specialists who work within the University Health Network in Toronto – Dr. Alon Vaisman, Dr. Susy Hota and Dr. Isaac Bogoch.

Hui DS, I Azhar E, Madani TA, et al. The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health - The latest 2019 novel coronavirus outbreak in Wuhan, China [published online ahead of print, 2020 Jan 14]. Int J Infect Dis. 2020;91:264–266. doi:10.1016/j.ijid.2020.01.009 - Free full-text

New England Journal of Medicine – 2019 Novel Coronavirus (2019-nCoV) - collection of articles and other resources on the 2019 Novel Coronavirus outbreak including clinical reports, management guidelines and commentary (Chinese translations available for some content).

NEJM Journal Watch - January 27, 2020 - 2019 Novel Coronavirus: First Reports Published -  Rajesh T. Gandhi, MD reviewing Zhu N et al. N Engl J Med 2020 Jan 24 Huang C et al. Lancet 2020 Jan 24 Chan JF-W et al. Lancet 2020 Jan 24

Paules CI, Marston HD, Fauci AS. Coronavirus Infections-More Than Just the Common Cold [published online ahead of print, 2020 Jan 23]. JAMA. 2020;10.1001/jama.2020.0757. doi:10.1001/jama.2020.0757 - Free full-text 

 

Guidelines and other information

International

About 2019 Novel Coronavirus (2019-nCoV) – Centers for Disease Control and Prevention. Updated January 28, 2020. Accessed February 4, 2020.

2019 novel coronavirus (2019-nCoV): interim guidance for healthcare professionals - Centers for Disease Control and Prevention. Updated February 2, 2020. Accessed February 4, 2020.

Interactive, global map tracking 2019-nCoV  - Johns Hopkins University. Updated January 30, 2020. Accessed February 4, 2020.

Coronavirus - World Health Organization. Updated January 29, 2020. Accessed February 4, 2020.

 

National

Information for physicians and the public on the coronavirus – Canadian Medical Association. Updated February 4, 2020. Accessed February 4, 2020.

Coronavirus Information and Resources – College of Family Physicians of Canada. Updated February 3, 2020. Accessed February 4, 2020.

2019 Novel Coronavirus infection (Wuhan, China): Outbreak update – Government of Canada. Updated February 4, 2020. Accessed February 4, 2020.

2019 Novel Coronavirus infection (Wuhan, China): For health professionals – Government of Canada. Updated February 3, 2020. Accessed February 4, 2020.

Novel Coronavirus in China: Travel Health Notice - Government of Canada. Updated January 31, 2020. Accessed February 4, 2020.

Coronavirus infection: Symptoms and treatment - Government of Canada. Updated January 21, 2020. Accessed February 4, 2020.

Information about Coronavirus – Infection Prevention and Control Canada. Updated January 30, 2020. Accessed February 4, 2020.

Infection Prevention and Control for Novel Coronavirus (2019-nCoV): Interim Guidance for Acute Healthcare Settings  - Public Health Agency of Canada. Updated February 3, 2020. Accessed February 4, 2020.

 

Provincial

Information on novel coronavirus - BC Centre on Disease Control. Updated February 4, 2020. Accessed February 4, 2020.

Novel Coronavirus (2019-nCoV) - Alberta Health Services. Updated February 4, 2020. Accessed February 4, 2020.

Novel Coronavirus (2019-nCoV) Guidance for Primary Care Providers in a Community Setting – Ontario Ministry of Health. Updated January 28, 2020. Accessed February 4, 2020.

Novel Coronavirus (2019-nCoV) - Public Health Ontario. Updated February 4, 2020. Accessed February 4, 2020.

 

Patient education

What you need to know about 2019-nCoV – Centers for Disease Control and Prevention. Updated January 28, 2020. Accessed February 4, 2020.

What to do if you are sick with 2019-nCoV - Centers for Disease Control and Prevention. Updated January 28, 2020. Accessed February 4, 2020.

Novel Corona Virus Infection - Elsevier Interactive Patient Education.  Updated January 23, 2020. Accessed February 4, 2020.

2019 Novel Coronavirus: Information sheetPublic Health Agency of Canada. Updated February 4, 2020. Accessed February 4, 2020.

 

Need more information or have a more focused clinical question on coronaviruses or any other clinical topic of interest? Contact the Ask a Librarian team to request a literature search.

 

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This material is for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice. The opinions stated by the authors are made in a personal capacity and do not necessarily reflect those of the Canadian Medical Association and its subsidiaries including Joule.  Feel passionate about physician-led innovation? Please connect with us at jouleinquiries@cma.ca.

About the author

Joule’s medical librarians are the professionals behind “Ask a Librarian”, a service for all CMA members looking for clinical search expertise. This experienced team of librarians can support you by searching on your behalf, teaching you effective search strategies or training you to use our clinical resources.

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