Ask a Librarian: COVID-19 (updated weekly)

Testing for COVID-19

Last updated: April 6, 2020 - Originally published: February 10, 2020

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Joule’s Ask a Librarian team has committed its skills to curate free evidence-based resources related to the current COVID-19 pandemic. This page will be updated regularly – the information and resources added most recently will be marked with an asterisk (*).

Visit the CMA’s COVID-19 page for the latest public health information and resources for physicians and patients. 

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Clinical summaries

DynaMed

Access DynaMed online or through the mobile app to get concise overviews and detailed recommendations, medical graphics and images, drug information from Micromedex and more.

COVID-19 (Novel Coronavirus) – Updated April 3, 2020

Description

  • acute respiratory disease caused by a novel coronavirus (SARS-CoV-2) first identified in December 2019 in Wuhan, Hubei Province, China and spreading worldwide1
  • SARS-CoV-2 is a member of beta genus coronaviruses closely related to SARS-CoV (Nat Microbiol 2020 Mar 2 early online)
  • common signs of COVID-19 include fever, cough, and shortness of breath1
  • there is no specific antiviral treatment for COVID-19, but supportive care may help to relieve symptoms and should include support of vital organ functions in severe cases1

Recent updates *

  • 3 Apr 2020: hydroxychloroquine sulfate with or without azithromycin may increase viral clearance of SARS-CoV-2 within 6 days in adults with COVID-19 (Int J Antimicrob Agents 2020 Mar 20 early online) View in topic

  • 1 Apr 2020: convalescent plasma transfusion reported to resolve acute respiratory distress syndrome in 4 of 5 critically ill adults with confirmed COVID-19, with weaning from mechanical ventilation in 3 patients within 2 weeks of transfusion (JAMA 2020 Mar 27 early online) View in topic
  • 1 Apr 2020: FDA issues Emergency Use Authorization permitting emergency usage of hydroxychloroquine sulfate from National Strategic Stockpile for treatment of COVID-19 in hospitalized adults and adolescents weighing ≥ 50 kg for whom clinical trials are not available or participation not feasible (FDA Fact Sheet 2020 Mar 28) View in topic

Topic Summary (CMA members can access full summaries via this link)

BMJ Best Practice

Coronavirus disease 2019 (COVID-19) – Literature review current through March 2020. This topic last updated: April 3, 2020.

UpToDate

Coronavirus disease 2019 (COVID-19) - Literature review current through: Feb 2020. This topic last updated: April 4, 2020.

Essential Evidence Plus*

Severe coronavirus infections (COVID-19, SARS) – one of the few summaries that compare COVID-19 and SARS, two related yet different types of coronavirus. This topic last updated: April 4, 2020.

 

Clinical information via ClinicalKey

ClinicalKey drives better care by delivering fast, concise answers, and deep access to evidence whenever, wherever you need it. ClinicalKey includes access to 1,000+ textbooks, 600 full-text journals, images, videos and customizable patient handouts across 30+ medical specialties

Novel Coronavirus Information Center  (Elsevier/ClinicalKey) - freely available and current information in English and Mandarin Chinese. Updated: April 3, 2020.

In ClinicalKey (CMA members only) search “COVID-19” for the latest articles from The Lancet, International Journal of Infectious Diseases, Journal of Infection and more.

Procedural Videos - Orotracheal Intubation (login required) 

Book chapters:

Gerber  Novel Coronavirus from Wuhan China, 2019-20, Update to Chapter 155, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, Ninth Edition (Elsevier, 2020) 

Coronaviruses, Including Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS), Chapter 155, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, Ninth Edition (Elsevier, 2020)

 

Articles, article collections and reviews

Annals of Internal Medicine - Content Related to Coronavirus 

BMJ - Coronavirus – collection of freely available news articles, opinion, timeline and a BMJ Best Practice summary.

Cambridge University Press – Coronavirus Free Access Collection. 

CMAJ – COVID-19 – CMAJ articles, podcasts and blogs on public health and policy.

Centre for Evidence-Based Medicine Oxford University – COVID-19 evidence service.

Cochrane Library - Coronavirus (COVID-19) – evidence relevant to critical care.

Evidence aid ‒ Coronavirus (COVID-19): Evidence Collection – summaries of relevant research. 

JAMA Coronavirus Disease 2019 (COVID-19) – collection of current articles and multimedia.

The Lancet COVID-19 Resource Centre – free access to COVID-19 content from across The Lancet journals.

LitCovid – the US National Library of Medicine’s curated literature hub for tracking up-to-date scientific information about the virus.

New England Journal of Medicine – 2019 Novel Coronavirus (2019-nCoV) collection of articles and other resources on the 2019 Novel Coronavirus outbreak including clinical reports, management guidelines and commentary (Chinese translations available for some content).

Oxford University Press – Free access to OUP resources on coronavirus and related topics. 

Springer-Nature - SARS-CoV-2 and COVID-19. 

Wiley Online Library - Covid-19: Novel Coronavirus Outbreak. 

 

Guidelines and other information

International

Coronavirus Disease 2019 (COVID-19): information for health care professionals – Centers for Disease Control and Prevention. Last reviewed April 1, 2020. Accessed April 6, 2020.

Interactive, global map tracking COVID-19 – Johns Hopkins University. Updated April 6, 2020. Accessed April 6, 2020.

Coronavirus disease (COVID-19) outbreak – World Health Organization. Updated April 3, 2020. Accessed April 6, 2020.

 

National

Clinical guideline search (CPG Infobase) – Joule, A Canadian Medical Association Company. Clinical Practice Guidelines on COVID-19/Coronavirus infections. Updated April 6, 2020. Accessed April 6, 2020.

2020 Information for physicians and the public on the coronavirus – Canadian Medical Association. Updated April 6, 2020. Accessed April 6, 2020.

COVID-19 Information and Resources – College of Family Physicians of Canada. Updated April 2, 2020. Accessed April 6, 2020.

Coronavirus disease (COVID-19): Outbreak update – Government of Canada. Updated April 5, 2020. Accessed April 6, 2020.

Coronavirus disease (COVID-19): For health professionals – Government of Canada. Updated April 3, 2020. Accessed April 6, 2020.

Coronavirus infection: Symptoms and treatment – Government of Canada. Updated April 3, 2020. Accessed April 6, 2020.

Information about Coronavirus – Infection Prevention and Control Canada. Updated April 5, 2020. Accessed April 6, 2020.

Infection prevention and control for coronavirus disease (COVID-19): Interim guidance for acute healthcare settings  – Public Health Agency of Canada. Updated February 24, 2020. Accessed April 6, 2020.

 

Provincial

British Columbia: 

Yukon: Information about Coronavirus Disease (COVID-19) for Yukoners – Government of Yukon. Updated April 3, 2020.  Accessed April 6, 2020.

Northwest Territories: Coronavirus Disease (COVID-19) – Government of Northwest Territories – Health and Social Services. Updated April 5, 2020. Accessed April 6, 2020.

Alberta: Novel Coronavirus (COVID-19) – Alberta Health Services. Updated April 5, 2020. Accessed April 6, 2020.

Saskatchewan: 2019 Novel Coronavirus (COVID-19) – Saskatchewan. No date. Accessed April 6, 2020.

Manitoba: 

Nunavut: COVID-19 (Novel Coronavirus) – Nunavut Department of Health. Updated April 1, 2020.  Accessed April 6, 2020.

Ontario:

Quebec: 

New Brunswick:  Coronavirus – Office of the Chief Medical Officer of Health (Public Health) New Brunswick. Updated April 5, 2020. Accessed April 6, 2020.

Nova Scotia: 

Prince Edward Island:

Newfoundland: COVID-19 Information – Newfoundland Health and Community Services. Updated April 5, 2020. Accessed April 6, 2020. 

 

Telemedicine and virtual care*

Virtual Care Playbook – Canadian Medical Association, College of Family Physicians, and Royal College of Physicians and Surgeons of Canada. March 30, 2020. Accessed April 6, 2020.

Telemedicine and virtual care guidelines – Royal College of Physicians and Surgeons of Canada. Updated Mar 30, 2020. Accessed April 6, 2020.

Virtual care and the 2019 Novel Coronavirus (COVID-19) – Ontario MD. No date. Accessed April 6, 2020.

 

Ethics and medical-legal resources*

COVID-19 Hub – advice, support, and medical-legal protection during the COVID-19 pandemic – Canadian Medical Protective Association. Updated April 6, 2020. Accessed April 6, 2020.

Ethics – BC Centre for Disease Control. Updated March 28, 2020. Accessed April 6, 2020.

Public Health Ethics and COVID-19: Selected Resources – Institut national de santé publique (Québec). Updated April 3, 2020. Accessed April 6, 2020.

Ethics Resources on the Coronavirus (COVID-19) - collection of articles and reports on ethics related to COVID-19, other coronaviruses and pandemics – Hastings Center. No date. Accessed April 6, 2020.

 

Patient education resources

COVID-19 Information for the public – Canadian Medical Association. Updated April 3, 2020. Accessed April 6, 2020.

What you need to know about coronavirus disease 2019 (COVID-19)  – Centers for Disease Control and Prevention. Updated March 20, 2020. Accessed April 60, 2020.

What to do if you are sick with coronavirus disease (COVID-19)  – Centers for Disease Control and Prevention. March 20, 2020. Accessed April 6, 2020.

Coronavirus Disease (COVID-19): Awareness resources (fact sheets and infographics available in many languages) – Public Health Agency of Canada. Updated April 4, 2020. Accessed April 6, 2020.

 

More literature searches

GoogleScholar search

Pubmed search

Trip database search (Turning research into practice)

 

Need more information or have a more focused clinical question on coronaviruses or any other clinical topic of interest? Contact the Ask a Librarian team to request a literature search.

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This material is for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice. The opinions stated by the authors are made in a personal capacity and do not necessarily reflect those of the Canadian Medical Association and its subsidiaries including Joule.  Feel passionate about physician-led innovation? Please connect with us at jouleinquiries@cma.ca.

 

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Joule’s medical librarians are the professionals behind “Ask a Librarian”, a service for all CMA members looking for clinical search expertise. This experienced team of librarians can support you by searching on your behalf, teaching you effective search strategies or training you to use our clinical resources.

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